DYNAMICS OF CHANGES IN THE FUNCTIONAL ACTIVITY OF NONSPECIFIC INFLAMMATORY FACTORS IN WIDESPREAD PERITONITIS

Summary. Aim. The determination of the impact developed complex treatment patients with peritonitis on functional state effector cells antimicrobial resistance during course disease.
 Materials and methods. study included toxic terminal stages (124 patients), who were treated in 2022. They divided into 3 groups. Group I (main) 39 (31.4 %) whose cytochrome C. II 41 (33.1 C Tivorel. comparison group consisted 44 (35.5 whom indicated drugs not used.
 Results. In I, 7th day was characterized by a significant decrease spontaneous activity neutrophil granulocytes (NG) NBT-test relative to initial values 2.21 times (p<0.001). However, 2.91 (p<0.001) increase induced NG determined. An monocytes determined 3.12 Indicators reaction exceeded 4.96 group, study, found 2.94 A 4.52-fold test baseline established NBT-test. These indicators 2.93 5.25 values, respectively.
 Conclusions. nitroblue tetrazolium recovery (NBT-test) are objective nonspecific inflammatory factors peritonitis.